Z. Jimmy Zhou, PhD

Jimmy Zhou's areas of interest include visual information processing, retinal physiology and synaptic circuitry, visual system development, human stem cell–derived retinal organoids, and human models of retinal physiology and pathophysiology. His experimental approach encompasses patch-clamp electrophysiology, two-photon imaging, optogenetics, visual stimulation, computational modeling, and AI-assisted connectomic circuit analysis with functional correlation. Zhou's work aligns with WTI's mission through neuro (visual) cognition and behavior, neuro (visual system) development, and neuro (retinal) computation.

electrophysiology ;  neural networks ;  optogenetics ;  two-photon imaging  

circuits ;  connectivity ;  physiology ;  sensory systems ;  synapses ;  vision  

Zhou has been studying retinal physiology, circuitry, and visual system development for over three decades. His lab currently focuses on integrating the cellular and synaptic physiology of retinal neurons with their connectomic architecture and transcriptomic signature to elucidate mechanisms of retinal function and disease. In 2008, he joined Yale as the Marvin L. Sears Professor and Vice Chair for Research in Ophthalmology and Visual Science. He is also a Professor of Cellular and Molecular Physiology and of Neuroscience.